Heat Therapy Intervention and Pulse Dose Itraconazole as Combination Treatment for Chromoblastomycosis: An Unusual Case Report

Authors

  • Sissy Department of Dermatology and Venereology, Faculty of Medicine and Health Sciences, Republic of Indonesian Defense University, Bogor, Indonesia
  • Clara Virginia Allun Faculty of Medicine and Health Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
  • Daniel Ahmad Romero Faculty of Medicine and Health Sciences, Republic of Indonesia Defense University, Bogor, Indonesia
  • Mahfudz Shidiq Faculty of Medicine and Health Sciences, Republic of Indonesia Defense University, Bogor, Indonesia

Keywords:

chromoblastomycosis, heat therapy, itraconazole pulse dose, case report

Abstract

Chromoblastomycosis (CBM) is a rare chronic fungal infection caused by dematiaceous fungi, presenting a significant challenge in Indonesia. This case involves a 54-year-old man who reported a lump on his right leg persisting for 10 years. Examination revealed multiple erythematous nodules with well-defined borders and a verrucous surface, forming a linear pattern around the ankle, some covered by brownish crusts. The patient denied itching and pain in the lesions. The initial diagnosis of chromoblastomycosis was confirmed through culture and histopathology. Treatment involved pulsed doses of intraconazole and heat therapy. Remarkably, lesions significantly improved after one month, underscoring the efficacy of combination therapy for chromoblastomycosis. Pulsed dose itraconazole enhances treatment compliance with its cost-effectiveness, while heat therapy, as a physical intervention, proves to be an easily administered option with promising efficacy. Considering the prolonged management required for CBM, it is imperative to factor in the patient's socioeconomic condition during treatment planning.

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Published

2024-01-03

How to Cite

Sissy, S., Virginia Allun, C. ., Ahmad Romero, D. ., & Shidiq, M. . (2024). Heat Therapy Intervention and Pulse Dose Itraconazole as Combination Treatment for Chromoblastomycosis: An Unusual Case Report. ASEAN Journal of Military and Preventive Medicine, 1(1), 23–30. Retrieved from http://journal.ajmpm.net/index.php/ojs/article/view/2

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